03552cam a22004578i 450000100090000000300080000900500170001700700030003400800410003701000170007802000300009502000270012502000270015203500130017904000320019204100080022404200080023205000220024008200120026210000280027424500780030225000460038026400410042630000510046733600260051833700280054433800270057250400510059950503890065052017010103965000150274065000160275565000340277165000460280565000380285165000400288965000260292965000240295565000540297965000610303323940592BJBSDDR20250804154323.0ta250724s2025 nyu 001 0 eng  a 2024041727 a9781668067666 (hardcover) a1668067668 (hardcover) z9781668067680q(ebook) a23940592 aDLCbengerdacBJBSDDRdDLC aeng apcc14aQP 85bT675s 202500a612.6/81 aTopol, Eric J., d1954-10aSuper agers :ban evidence-based approach to longevity /cEric Topol, MD. aFirst Simon & Schuster hardcover edition  1aNew York :bSimon & Schuster,c2025. a452 pages : billustrations, charts ; c25 cm. atextbtxt2rdacontent aunmediatedbn2rdamedia avolumebnc2rdacarrier aIncludes bibliographical references and index.0 aPart I The age of health span. A tale of two patients ; It's in your genes? ; Lifestyle+ Part II Chronic killers. Obesity and diabetes ; Cardiovascular disease ; Cancer ; Neurodegeneration Part III Great implications. Curing rare diseases ; Controlling our immune system ; Defeating infectious agents ; Promoting mental health Part IV Thinking ahead. Changing aging ; The path forward a"One of the most respected, celebrated, and influential medical researchers in the world gives a guided tour of the revolution in longevity science that is exploding now. This is an evidence-based approach to longevity in a market drenched in snake oil-Eric Topol doesn't promise a silver bullet to magically stop the aging process, he shows how preventing the development of killer chronic diseases like obesity, heart disease, cancer and neurodegeneration is completely changing what "old age" can be. And we can start long before middle age-or long after. Dr. Topol shows how and why you can deal with chronic problems now instead of waiting until it is too late. Breakthrough treatments have been developed from new tools, new understanding of how our personal genomes work, and what AI can see in our health data. We can now engineer cells, build proteins and find drugs that make us live longer, better. Many of these treatments are on the shelf now-or soon will be-and improving fast. Our author is the ultimate guide because he participated in developing and testing many of them. The first part of the book "The New Age of Healthspan" describes inspiring patients aged 90+, sets out the dimensions of the new advances in the treatments of age related diseases, and details an expanded definition of what a healthy lifestyle means now-good sleep, diet, exercise, sure, but much beyond. He calls it Lifestyle+. He then turns to the "Chronic Killers"-Obesity/Diabetes, Heart Disease, Cancer, and Neurodegeneration. Parts on the "Big Collateral Implications" and "Thinking Ahead" follow and include ways we might eventually come to reverse the aging process itself"--cProvided by publisher. 0aLongevity. 4aLongevidad. 0aAgingxPhysiological aspects. 4aEnvejecimiento xAspectos fisiológicos  0aOlder peoplexHealth and hygiene. 4aPersonas mayores xSalud e higiene  0aMedicine, Preventive. 4aMedicina preventiva 0aArtificial intelligencexIndustrial applications. 4aAplicaciones industriales de la inteligencia artificial