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  <titleInfo>
    <title>Robustness and evolvability in living systems</title>
  </titleInfo>
  <name type="personal">
    <namePart>Wagner, Andreas</namePart>
    <namePart type="date">1967-</namePart>
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  <originInfo>
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    <place>
      <placeTerm type="text">Princeton, N.J</placeTerm>
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    <publisher>Princeton University Press</publisher>
    <dateIssued>c2005</dateIssued>
    <dateIssued encoding="marc">2005</dateIssued>
    <issuance>monographic</issuance>
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  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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  <physicalDescription>
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    <extent>xii, 367 p. : ill. ; 24 cm.</extent>
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  <tableOfContents>Introduction -- The genetic alphabet -- The genetic code -- RNA structure -- Proteins and point mutations -- Proteins and recombination -- Regulatory DNA regions and their reorganization in evolution -- Metabolic pathways -- Metabolic networks -- Drosophila segmentation and other gene regulatory networks -- Phenotypic traits, cryptic variation, and human diseases -- The many ways of building the same body -- Neutral spaces -- Evolvability and neutral mutations -- Redundancy of parts or distributed robustness? -- Robustness as an evolved adaptation to mutations -- Robustness as an evolved adapatation to environmental change and noise -- Robustness and fragility: advantages to variation and trade-offs -- Robustness in natural systems and self-organization -- Robustness in man-made systems.</tableOfContents>
  <note type="statement of responsibility">Andreas Wagner.</note>
  <note>Includes bibliographical references (p. [323]-358) and index.</note>
  <subject authority="lcsh">
    <topic>Molecular evolution</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Mutation (Biology)</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Biological systems</topic>
    <topic>Stability</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Robust control</topic>
  </subject>
  <subject authority="mesh">
    <topic>Evolution, Molecular</topic>
  </subject>
  <subject authority="mesh">
    <topic>Genomic Instability</topic>
  </subject>
  <subject authority="mesh">
    <topic>Mutation</topic>
  </subject>
  <subject authority="larpcal">
    <topic>Mutaðcäao genâetica</topic>
  </subject>
  <subject authority="larpcal">
    <topic>Evoluðcäao molecular</topic>
  </subject>
  <subject authority="rvm">
    <topic>âEvolution molâeculaire</topic>
  </subject>
  <subject authority="rvm">
    <topic>Mutation (Biologie)</topic>
  </subject>
  <subject authority="rvm">
    <topic>Systáemes biologiques</topic>
    <topic>Stabilitâe</topic>
  </subject>
  <subject authority="rvm">
    <topic>Commande robuste</topic>
  </subject>
  <classification authority="lcc">QH 390 W132r 2005</classification>
  <classification authority="ddc">572.8/38</classification>
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    <titleInfo>
      <title>Princeton studies in complexity</title>
    </titleInfo>
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  <identifier type="isbn">0691122407 (cloth : alk. paper)</identifier>
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